ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tmed7

Full Name:

transmembrane emp24 protein transport domain containing 7

Alias:

3930401E15Rik|5830493P14Rik|AU044611|AW545765|TRAM

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

18 C

Physical Location:

46710987-46722851 on NC_000084.4, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 51014 Symbol (Name): TMED7 (transmembrane emp24 protein transport domain containing 7)

Ortholog Status:

The human GeneID 51014 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		3930401E15Rik
Original ID2:		AI846109

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_128959.5	XP_128959.3	NC_000084.4 range: 46710987..46722851, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	RCA (16141072)
GO:0008320	protein transmembrane transporter activity	Molecular Function	RCA (16141072)
GO:0006886	intracellular protein transport	Biological Process	RCA (16141072)