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Gene Information
Gene ID:68097
Symbol:Dynll2
Full Name:dynein light chain LC8-type 2
Alias:1700064A15Rik|6720463E02Rik|C87222|Dlc2
Organism:Mus musculus (Mouse)
Chromosome:11
Genetic Location:11 C
Physical Location:87793034-87801006 on NC_000077.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 140735    Symbol (Name): DYNLL2 (dynein, light chain, LC8-type 2)
Ortholog Status:The human GeneID 140735 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:6720463E02Rik
Original ID2:AI836322
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_026556.3NP_080832.1NC_000077.5 range: 87793034..87801006, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005875microtubule associated complexCellular ComponentRCA (16141072)
GO:0030286dynein complexCellular ComponentNAS (14561217)
GO:0016459myosin complexCellular ComponentIDA (14561217)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005874microtubuleCellular ComponentIEA
GO:0003774motor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (11546872)
GO:0003777microtubule motor activityMolecular FunctionRCA (16141072)
GO:0007017microtubule-based processBiological ProcessRCA (16141072)
GO:0046907intracellular transportBiological ProcessNAS (14561217)
Other Database Cross Links
NCBI Entrez Gene:68097
MGI:
Ensembl:ENSMUSG00000020483
dbSNP:Dynll2
AceView:Dynll2