ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Trim13

Full Name:

tripartite motif-containing 13

Alias:

3110001L12Rik|CAR|LEU5|RNF77|Rfp2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D1

Physical Location:

62218630-62224779 on NC_000080.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10206 Symbol (Name): TRIM13 (tripartite motif-containing 13)

Ortholog Status:

The human GeneID 10206 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Trim13
Original ID2:		AI592541

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_023233.2	NP_075722.1	NC_000080.5 range: 62218630..62224779

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	IDA (11331580)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005515	protein binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	RCA (12466851)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007049	cell cycle	Biological Process	IEA
GO:0009987	cellular process	Biological Process	RCA (12466851)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA