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Dataset Description
  • Dataset Name: 15745951
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 277
  • Tissue: Nucleus accumbens, prefrontal cortex, and ventral tegmental area
  • Phenotype: Acute ethanol response
  • Publication: Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
  • Dataset Summary: The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

    Gene list of this dataset (277 genes)
    Page: 1 2 3 4 5 6 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    16476JunJun oncogene4 C5-C7|4 44.6 cMJunX12761
    16480Jupjunction plakoglobin11 D|11 60.0 cMJupM90365
    16500Kcnb1potassium voltage gated channel, Shab-related subfamily, member 12 H3|2 97.0 cMKcnb1M64228
    16502Kcnc1potassium voltage gated channel, Shaw-related subfamily, member 17 B4|7 23.5 cMKcnc1Y07521
    16508Kcnd2potassium voltage-gated channel, Shal-related family, member 26 A2-A3.1|6 7.2 cMKcnd2AI839615
    16531Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 114 A3Kcnma1U09383
    17060BlnkB-cell linker19 C3|19 31.0 cMBlnkAF068182
    17153Malmyelin and lymphocyte protein, T-cell differentiation protein2 F1MalY07812
    17181Matn2matrilin 215 B3.3Matn2U69262
    17184Matr3matrin 318 C|18 15.0 cMMatr3AI835367
    17196Mbpmyelin basic protein18 E2-E4|18 55.0 cMMbpL07508
    17196Mbpmyelin basic protein18 E2-E4|18 55.0 cMMbpM11533
    17260Mef2cmyocyte enhancer factor 2C13 C3|13 45.0 cMMef2cAI595996
    17260Mef2cmyocyte enhancer factor 2C13 C3|13 45.0 cMMef2cL13171
    17433Mobpmyelin-associated oligodendrocytic basic protein9 F4|9 69.0 cMMobpAI834776
    17433Mobpmyelin-associated oligodendrocytic basic protein9 F4|9 69.0 cMMobpAI839662
    17433Mobpmyelin-associated oligodendrocytic basic protein9 F4|9 69.0 cMMobpU81317
    17441Mogmyelin oligodendrocyte glycoprotein17 C|17 20.34 cMMogL20942
    17475Mpdzmultiple PDZ domain protein4 C3|4 38.6 cMMpdzAJ131869
    17748Mt1metallothionein 18 C5|8 45.0 cMMt1V00835
    17750Mt2metallothionein 28 C5|8 45.0 cMMt2K02236
    17776Mast2microtubule associated serine/threonine kinase 24 C7Mast2U02313
    17886Myh9myosin, heavy polypeptide 9, non-muscle15 E1|15 43.3 cMMyh9AI505453
    17912Myo1bmyosin IB1 C1.1|1 24.8 cMMyo1bL00923
    17988Ndrg1N-myc downstream regulated gene 115 D2Ndrg1U52073
    17988Ndrg1N-myc downstream regulated gene 115 D2Ndrg1U60593
    17999Nedd4neural precursor cell expressed, developmentally down-regulated gene 49 D|9 40.0 cMNedd4AF026124
    17999Nedd4neural precursor cell expressed, developmentally down-regulated gene 49 D|9 40.0 cM---U96635
    18028Nfibnuclear factor I/B4 C4-C6|4 38.6 cMNfibY07685
    18028Nfibnuclear factor I/B4 C4-C6|4 38.6 cMNfibY07686
    18111Nnatneuronatin2 H1|2 88.0 cMNnatX83569
    18164Nptx1neuronal pentraxin 111 E1-E2|11 75.0 cMNptx1U62021
    18481Pak3p21 (CDKN1A)-activated kinase 3X F2Pak3U39738
    18484Pampeptidylglycine alpha-amidating monooxygenase1 D|1 57.5 cMPamU79523
    18516Pbx3pre B-cell leukemia transcription factor 32 B|2 22.0 cMPbx3AF020200
    18519Pcafp300/CBP-associated factor17 C|17 30.0 cMPcafAW047728
    18536Pcm1pericentriolar material 18 A4|8 22.5 cMPcm1AF039021
    18546Pcp4Purkinje cell protein 416 C4|16 69.9 cMPcp4X17320
    18563Pcxpyruvate carboxylase19 A|19 0.0 cMPcxM97957
    18574Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent15 F3Pde1bAF023343
    18607Pdpk13-phosphoinositide dependent protein kinase-117 A3.3Pdpk1AW122388
    18619Penk1preproenkephalin 14 A1|4 0.8 cMPenk1M55181
    18807Pld3phospholipase D family, member 37 A3Pld3D87990
    18823Plp1proteolipid protein (myelin) 1X F1-F2|X 56.0 cMPlpM16472
    18823Plp1proteolipid protein (myelin) 1X F1-F2|X 56.0 cMPlpM37335
    18999Pou5f1POU domain, class 5, transcription factor 117 B1|17 19.23 cMPou5f1AV214633
    19017Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha5 C1Ppargc1aAF049330
    19053Ppp2cbprotein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform8 A4|8 20.0 cMPpp2cbZ67746
    19085Prkar1bprotein kinase, cAMP dependent regulatory, type I beta5 G2|5 82.0 cMPrkar1bAW125016
    19211Ptenphosphatase and tensin homolog19 C1|19 24.5 cMPtenU92437
    Page: 1 2 3 4 5 6 list all