ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ndrg1

Full Name:

N-myc downstream regulated gene 1

Alias:

CAP43|CMT4D|DRG1|HMSNL|NMSL|Ndr1|Ndrl|PROXY1|RTP|TDD5

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 D2

Physical Location:

66760879-66801202 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10397 Symbol (Name): NDRG1 (N-myc downstream regulated gene 1)

Ortholog Status:

The human GeneID 10397 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Ndrg1
Original ID2:		U52073

Gene Information

Original ID1:		Ndrg1
Original ID2:		U60593

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008681.2	NP_032707.2	NC_000081.5 range: 66760879..66801202, complement

Gene Ontology (GO) Annotation