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Gene Information
Gene ID:17196
Symbol:Mbp
Full Name:myelin basic protein
Alias:C76307|Hmbpr|R75289|golli-mbp|mld|shi
Organism:Mus musculus (Mouse)
Chromosome:18
Genetic Location:18 E2-E4|18 55.0 cM
Physical Location:82644514-82755028 on NC_000084.5
Gene Type:protein-coding
Human Ortholog:GeneID: 4155    Symbol (Name): MBP (myelin basic protein)
Ortholog Status:The human GeneID 4155 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Mbp
Original ID2:L07508
Gene Information
Original ID1:Mbp
Original ID2:M11533
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001025245.1NP_001020416.1NC_000084.5 range: 82644514..82755028
NM_001025251.2NP_001020422.1NC_000084.5 range: 82644514..82755028
NM_001025254.2NP_001020425.1NC_000084.5 range: 82644514..82755028
NM_001025255.2NP_001020426.1NC_000084.5 range: 82644514..82755028
NM_001025256.2NP_001020427.1NC_000084.5 range: 82644514..82755028
NM_001025258.2NP_001020429.1NC_000084.5 range: 82644514..82755028
NM_001025259.2NP_001020430.1NC_000084.5 range: 82644514..82755028
NM_010777.3NP_034907.1NC_000084.5 range: 82644514..82755028
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0043209myelin sheathCellular ComponentIDA (1694232|16405874|16421295)
GO:0043025cell somaCellular ComponentIDA (16421295)
GO:0042995cell projectionCellular ComponentIDA (16421295)
GO:0033269internode region of axonCellular ComponentIDA (16421295)
GO:0016020membraneCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0019911structural constituent of myelin sheathMolecular FunctionIEA
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0042552myelinationBiological ProcessIDA (14614079)
Other Database Cross Links
NCBI Entrez Gene:17196
MGI:
Ensembl:ENSMUSG00000041607
dbSNP:Mbp
AceView:Mbp