ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Matn2

Full Name:

matrilin 2

Alias:

Crtm2|MGC102477|matrilin-2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 B3.3

Physical Location:

34236435-34365996 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4147 Symbol (Name): MATN2 (matrilin 2)

Ortholog Status:

The human GeneID 4147 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Matn2
Original ID2:		U69262

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016762.2	NP_058042.2	NC_000081.5 range: 34236435..34365996

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IDA (11102754)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)