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Gene Information
Gene ID:17181
Full Name:matrilin 2
Organism:Mus musculus (Mouse)
Genetic Location:15 B3.3
Physical Location:34236435-34365996 on NC_000081.5
Gene Type:protein-coding
Human Ortholog:GeneID: 4147    Symbol (Name): MATN2 (matrilin 2)
Ortholog Status:The human GeneID 4147 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Matn2
Original ID2:U69262
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016762.2NP_058042.2NC_000081.5 range: 34236435..34365996
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005578proteinaceous extracellular matrixCellular ComponentIDA (11102754)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
Other Database Cross Links
NCBI Entrez Gene:17181