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Gene Information
Gene ID:66881
Full Name:prenylcysteine oxidase 1
Organism:Mus musculus (Mouse)
Genetic Location:6 D1
Physical Location:86336850-86347113 on NC_000072.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 51449    Symbol (Name): PCYOX1 (prenylcysteine oxidase 1)
Ortholog Status:The human GeneID 51449 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Pcyox1
Original ID2:AI850953
Dataset Information
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_025823.4NP_080099.1NC_000072.5 range: 86336850..86347113, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0005764lysosomeCellular ComponentIEA
GO:0001735prenylcysteine oxidase activityMolecular FunctionIMP (12151402)
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0030328prenylcysteine catabolic processBiological ProcessIMP (12151402)
Other Database Cross Links
NCBI Entrez Gene:66881