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Gene Information
Gene ID:20451
Symbol:St8sia3
Full Name:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Alias:AI847333|ST8SiaIII|Siat8c
Organism:Mus musculus (Mouse)
Chromosome:18
Genetic Location:18 E1
Physical Location:64425041-64435797 on NC_000084.5
Gene Type:protein-coding
Human Ortholog:GeneID: 51046    Symbol (Name): ST8SIA3 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3)
Ortholog Status:The human GeneID 51046 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Siat8c
Original ID2:X80502
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009182.2NP_033208.2NC_000084.5 range: 64425041..64435797
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentRCA (16141072)
GO:0030173integral to Golgi membraneCellular ComponentIEA
GO:0003828alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activityMolecular FunctionIDA (7782326)
GO:0008373sialyltransferase activityMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0016757transferase activity, transferring glycosyl groupsMolecular FunctionIEA
GO:0006486protein amino acid glycosylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:20451
MGI:
Ensembl:ENSMUSG00000056812
dbSNP:St8sia3
AceView:St8sia3