ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Rad23b

Full Name:

RAD23b homolog (S. cerevisiae)

Alias:

0610007D13Rik|AV001138|mHR23B|p58

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 B3

Physical Location:

55362928-55404083 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5887 Symbol (Name): RAD23B (RAD23 homolog B (S. cerevisiae))

Ortholog Status:

The human GeneID 5887 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Rad23b
Original ID2:		X92411

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009011.4	NP_033037.2	NC_000070.5 range: 55362928..55404083

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043234	protein complex	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	IEA
GO:0003684	damaged DNA binding	Molecular Function	IEA
GO:0006289	nucleotide-excision repair	Biological Process	IEA
GO:0006281	DNA repair	Biological Process	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0006974	response to DNA damage stimulus	Biological Process	IDA (12815074)
GO:0007283	spermatogenesis	Biological Process	IMP (11809813)
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IEA
GO:0006464	protein modification process	Biological Process	IEA