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Gene Information
Gene ID:232798
Symbol:Leng8
Full Name:leukocyte receptor cluster (LRC) member 8
Alias:AW049671
Organism:Mus musculus (Mouse)
Chromosome:7
Genetic Location:7 A1
Physical Location:4088657-4099774 on NC_000073.5
Gene Type:protein-coding
Human Ortholog:GeneID: 114823    Symbol (Name): LENG8 (leukocyte receptor cluster (LRC) member 8)
Ortholog Status:The human GeneID 114823 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Leng8
Original ID2:AI851703
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_172736.3NP_766324.1NC_000073.5 range: 4088657..4099774
Other Database Cross Links
NCBI Entrez Gene:232798
MGI:
Ensembl:ENSMUSG00000035545
dbSNP:Leng8
AceView:Leng8