| Gene Information |
| Gene ID: | | 20743 |
| Symbol: | | Spnb3 |
| Full Name: | | spectrin beta 3 |
| Alias: | | KIAA0302|MGC99874|mKIAA0302 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 19 |
| Genetic Location: | | 19 A|19 0.0 cM |
| Physical Location: | | 4711222-4752351 on NC_000085.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 6712 Symbol (Name): SPTBN2 (spectrin, beta, non-erythrocytic 2) |
| Ortholog Status: | | The human GeneID 6712 is also in human dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | Spnb3 | | Original ID2: | | AF026489 |
| | Dataset Information | | Name: | | 15745951 | | Method: | | Microarray | | Tissue: | | Nucleus accumbens, prefrontal cortex, and ventral tegmental area | | Phenotype: | | Acute ethanol response | | Publication: | | Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed | | Summary: | | The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0003779 | actin binding | Molecular Function | IEA | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 20743 |
| MGI: | |
| Ensembl: | | ENSMUSG00000067889 |
| dbSNP: | | Spnb3 |
| AceView: | | Spnb3 |
