Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:20743
Symbol:Spnb3
Full Name:spectrin beta 3
Alias:KIAA0302|MGC99874|mKIAA0302
Organism:Mus musculus (Mouse)
Chromosome:19
Genetic Location:19 A|19 0.0 cM
Physical Location:4711222-4752351 on NC_000085.5
Gene Type:protein-coding
Human Ortholog:GeneID: 6712    Symbol (Name): SPTBN2 (spectrin, beta, non-erythrocytic 2)
Ortholog Status:The human GeneID 6712 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Spnb3
Original ID2:AF026489
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_021287.1NP_067262.1NC_000085.5 range: 4711222..4752351
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0003779actin bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:20743
MGI:
Ensembl:ENSMUSG00000067889
dbSNP:Spnb3
AceView:Spnb3