ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Stmn2

Full Name:

stathmin-like 2

Alias:

AI159727|SCG10|Scgn10|Stmb2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

3 A1|3 6.6 cM

Physical Location:

8509526-8561603 on NC_000069.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11075 Symbol (Name): STMN2 (stathmin-like 2)

Ortholog Status:

The human GeneID 11075 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Stmn2
Original ID2:		AI840972

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025285.2	NP_079561.1	NC_000069.5 range: 8509526..8561603

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0030426	growth cone	Cellular Component	IDA (15581637)
GO:0042995	cell projection	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (15581637)
GO:0007242	intracellular signaling cascade	Biological Process	IEA