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Gene Information
Gene ID:12896
Symbol:Cpt2
Full Name:carnitine palmitoyltransferase 2
Alias:AI323697|CPTII
Organism:Mus musculus (Mouse)
Chromosome:4
Genetic Location:4 C7|4 54.4 cM
Physical Location:107576586-107596138 on NC_000070.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 1376    Symbol (Name): CPT2 (carnitine palmitoyltransferase II)
Ortholog Status:The human GeneID 1376 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Cpt2
Original ID2:AV266650
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_009949.2NP_034079.2NC_000070.5 range: 107576586..107596138, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentIDA (14651853)
GO:0016020membraneCellular ComponentIEA
GO:0004095carnitine O-palmitoyltransferase activityMolecular FunctionIEA
GO:0008415acyltransferase activityMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0006629lipid metabolic processBiological ProcessIEA
GO:0006631fatty acid metabolic processBiological ProcessIEA
GO:0006810transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:12896
MGI:
Ensembl:ENSMUSG00000028607
dbSNP:Cpt2
AceView:Cpt2