ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Col6a1

Full Name:

collagen, type VI, alpha 1

Alias:

AI747156|Col6a-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

10 41.1 cM

Physical Location:

76171536-76188788 on NC_000076.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1291 Symbol (Name): COL6A1 (collagen, type VI, alpha 1)

Ortholog Status:

The human GeneID 1291 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Col6a1
Original ID2:		X66405

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009933.3	NP_034063.1	NC_000076.5 range: 76171536..76188788, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0006817	phosphate transport	Biological Process	IEA
GO:0007155	cell adhesion	Biological Process	IEA