ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Prosc

Full Name:

proline synthetase co-transcribed

Alias:

1700024N20Rik|2200002F22Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 A3

Physical Location:

28153026-28166603 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11212 Symbol (Name): PROSC (proline synthetase co-transcribed homolog (bacterial))

Ortholog Status:

The human GeneID 11212 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		1700024N20Rik
Original ID2:		AW227620

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation