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Gene Information
Gene ID:102693
Symbol:Phldb1
Full Name:pleckstrin homology-like domain, family B, member 1
Alias:AU041016|D330037A14Rik|Ll5a|MGC32394
Organism:Mus musculus (Mouse)
Chromosome:9
Genetic Location:9 A5.2
Physical Location:44494390-44543276 on NC_000075.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 23187    Symbol (Name): PHLDB1 (pleckstrin homology-like domain, family B, member 1)
Ortholog Status:The human GeneID 23187 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D330037A14Rik
Original ID2:AI854506
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_153537.3NP_705765.3NC_000075.5 range: 44494390..44543276, complement
Other Database Cross Links
NCBI Entrez Gene:102693
MGI:
Ensembl:ENSMUSG00000048537
dbSNP:Phldb1
AceView:Phldb1