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Gene Information
Gene ID:105445
Symbol:Dock9
Full Name:dedicator of cytokinesis 9
Alias:AA959601|AW538057|B230309H04Rik|D14Wsu89e|Zizimin1|mKIAA1058
Organism:Mus musculus (Mouse)
Chromosome:14
Genetic Location:14 E5|14 67.0 cM
Physical Location:121941260-122097638 on NC_000080.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 23348    Symbol (Name): DOCK9 (dedicator of cytokinesis 9)
Ortholog Status:The human GeneID 23348 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D14Wsu89e
Original ID2:AW125299
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001081039.1NP_001074508.1NC_000080.5 range: 121941260..122097638, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005085guanyl-nucleotide exchange factor activityMolecular FunctionIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityMolecular FunctionIDA (15710388)
GO:0005525GTP bindingMolecular FunctionIEA
GO:0017048Rho GTPase bindingMolecular FunctionIPI (15710388)
GO:0051020GTPase bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:105445
MGI:
Ensembl:ENSMUSG00000025558
dbSNP:Dock9
AceView:Dock9