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Gene Information
Gene ID:10449
Symbol:ACAA2
Full Name:acetyl-Coenzyme A acyltransferase 2
Alias:DSAEC|FLJ35992|FLJ95265
Organism:Homo sapiens (Human)
Chromosome:18
Genetic Location:18q21.1
Physical Location:45563872-45593899 on NC_000018.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D16294
Fold Change:2.04
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006111.2NP_006102.2NC_000018.8 range: 45563872..45593899, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentNAS (8241273)
GO:0003988acetyl-CoA C-acyltransferase activityMolecular FunctionNAS (8241273)
GO:0008415acyltransferase activityMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0006629lipid metabolic processBiological ProcessIEA
GO:0006631fatty acid metabolic processBiological ProcessIEA
GO:0006695cholesterol biosynthetic processBiological ProcessNAS (8241273)
GO:0008152metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:10449
HGNC:83
Ensembl:ENSG00000167315
MIM:604770
HPRD:10380
HuGE Navigator:10449
dbSNP:ACAA2
GeneCard:ACAA2
AceView:ACAA2