ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

IFITM2

Full Name:

interferon induced transmembrane protein 2 (1-8D)

Alias:

1-8D

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11p15.5

Physical Location:

298106-299409 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X57351
Fold Change:		2.47

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006435.2	NP_006426.2	NC_000011.8 range: 298106..299409

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND (6548414)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0003674	molecular_function	Molecular Function	ND (6548414)
GO:0005515	protein binding	Molecular Function	IPI (15231747)
GO:0006955	immune response	Biological Process	TAS (1906403)
GO:0008150	biological_process	Biological Process	ND (6548414)
GO:0009607	response to biotic stimulus	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

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