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Gene Information
Gene ID:10634
Symbol:GAS2L1
Full Name:growth arrest-specific 2 like 1
Alias:GAR22|MGC17243
Organism:Homo sapiens (Human)
Chromosome:22
Genetic Location:22q12.2
Physical Location:28032996-28038773 on NC_000022.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.322852
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006478.3NP_006469.2NC_000022.9 range: 28032996..28038773
NM_152236.1NP_689422.1NC_000022.9 range: 28032996..28038773
NM_152237.1NP_689423.1NC_000022.9 range: 28032996..28038773
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005856cytoskeletonCellular ComponentIEA
GO:0007050cell cycle arrestBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:10634
HGNC:16955
Ensembl:ENSG00000185340
MIM:602128
HPRD:03676
HuGE Navigator:10634
dbSNP:GAS2L1
GeneCard:GAS2L1
AceView:GAS2L1