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Dataset Description
  • Dataset Name: 16292326
  • Species: Human
  • Method: Microarray
  • No. of Genes: 303
  • Tissue: Frontal cortex
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
  • Dataset Summary: In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

    Gene list of this dataset (303 genes)
    Page: 1 2 3 4 5 6 7 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    10888GPR83G protein-coupled receptor 8311q21Hs.272385 
    11086ADAM29ADAM metallopeptidase domain 294q34Hs.126838 
    114885OSBPL11oxysterol binding protein-like 113q21Hs.477440 
    1687DFNA5deafness, autosomal dominant 57p15Hs.520708 
    183AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)1q42-q43Hs.19383 
    22848AAK1AP2 associated kinase 12p14Hs.468878 
    255330C3orf46chromosome 3 open reading frame 463q21.3Hs.145435 
    2993GYPAglycophorin A (MNS blood group)4q28.2-q31.1Hs.434973 
    5624PROCprotein C (inactivator of coagulation factors Va and VIIIa)2q13-q14Hs.224698 
    64084CLSTN2calsyntenin 23q23-q24Hs.158529 
    6442SGCAsarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)17q21Hs.463412 
    79158GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits12q23.2Hs.46850 
    8396PIP4K2Bphosphatidylinositol-5-phosphate 4-kinase, type II, beta17q12Hs.260603 
    8542APOL1apolipoprotein L, 122q13.1Hs.114309 
    8767RIPK2receptor-interacting serine-threonine kinase 28q21Hs.103755 
    10085EDIL3EGF-like repeats and discoidin I-like domains 35q14Hs.482730 
    10128LRPPRCleucine-rich PPR-motif containing2p21Hs.368084 
    10152ABI2abl interactor 22q33Hs.471156 
    10208USPL1ubiquitin specific peptidase like 113q12-q14Hs.533831 
    1022CDK7cyclin-dependent kinase 75q12.1Hs.184298 
    1027CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)12p13.1-p12Hs.238990 
    10351ABCA8ATP-binding cassette, sub-family A (ABC1), member 817q24Hs.58351 
    10471PFDN6prefoldin subunit 66p21.3Hs.446374 
    10521DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 1722q13.1Hs.528305 
    10657KHDRBS1KH domain containing, RNA binding, signal transduction associated 11p32Hs.445893 
    10979FERMT2fermitin family homolog 2 (Drosophila)14q22.2Hs.509343 
    11083DIDO1death inducer-obliterator 120q13.33Hs.517172 
    11215AKAP11A kinase (PRKA) anchor protein 1113q14.11Hs.105105 
    1182CLCN3chloride channel 34q33Hs.481186 
    122060SLAIN1SLAIN motif family, member 113q22.3Hs.349955 
    1267CNP2',3'-cyclic nucleotide 3' phosphodiesterase17q21Hs.273621 
    1371CPOXcoproporphyrinogen oxidase3q12Hs.476982 
    138311FAM69Bfamily with sequence similarity 69, member B9q34.3Hs.495480 
    1514CTSL1cathepsin L19q21-q22Hs.418123 
    1593CYP27A1cytochrome P450, family 27, subfamily A, polypeptide 12q33-qterHs.516700 
    1655DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 517q21Hs.279806 
    1657DMXL1Dmx-like 15q22Hs.181042 
    167153PAPD4PAP associated domain containing 45q14.1Hs.418198 
    1781DYNC1I2dynein, cytoplasmic 1, intermediate chain 22q31.1Hs.546250 
    222068TMED4transmembrane emp24 protein transport domain containing 47p13Hs.510745 
    23041MON2MON2 homolog (S. cerevisiae)12q14.1Hs.389378 
    23111SPG20spastic paraplegia 20 (Troyer syndrome)13q13.3Hs.440414 
    23232TBC1D12TBC1 domain family, member 1210q23.33Hs.500598 
    23250ATP11AATPase, class VI, type 11A13q34Hs.29189 
    23258RAB6IP1RAB6 interacting protein 111p15.4Hs.501857 
    Page: 1 2 3 4 5 6 7 list all