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Dataset Description
  • Dataset Name: 16292326
  • Species: Human
  • Method: Microarray
  • No. of Genes: 303
  • Tissue: Frontal cortex
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
  • Dataset Summary: In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

    Gene list of this dataset (303 genes)
    Page: 1 2 3 4 5 6 7 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    7844RNF103ring finger protein 1032p11.2Hs.469199 
    79157MFSD11major facilitator superfamily domain containing 1117q25Hs.73965 
    79612NARG1LNMDA receptor regulated 1-like13q14.11Hs.512914 
    79993ELOVL7ELOVL family member 7, elongation of long chain fatty acids (yeast)5q12.1Hs.274256 
    8027STAMsignal transducing adaptor molecule (SH3 domain and ITAM motif) 110p14-p13Hs.441498 
    80821DDHD1DDHD domain containing 114q21Hs.513260 
    81566FAM130A1family with sequence similarity 130, member A112q13.11-q13.12Hs.524425 
    825CAPN3calpain 3, (p94)15q15.1-q21.1Hs.143261 
    8301PICALMphosphatidylinositol binding clathrin assembly protein11q14Hs.163893 
    831CASTcalpastatin5q15Hs.440961 
    84061MAGT1magnesium transporter 1Xq21.1Hs.323562 
    84181CHD6chromodomain helicase DNA binding protein 620q12Hs.371979 
    84188FAR1fatty acyl CoA reductase 111p15.2Hs.501991 
    84251SGIP1SH3-domain GRB2-like (endophilin) interacting protein 11p31.3Hs.132121 
    85315PAQR8progestin and adipoQ receptor family member VIII6p12.1Hs.239388 
    85476GFM1G elongation factor, mitochondrial 13q25.1-q26.2Hs.518355 
    8609KLF7Kruppel-like factor 7 (ubiquitous)2q32Hs.471221 
    8612PPAP2Cphosphatidic acid phosphatase type 2C19p13Hs.465506 
    8658TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase8p23.1Hs.370267 
    8761PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)1p32-p36Hs.169900 
    8925HERC1hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 115q22Hs.210385 
    8939FUBP3far upstream element (FUSE) binding protein 39q34.11-q34.12Hs.98751 
    89910UBE3Bubiquitin protein ligase E3B12q24.11Hs.374067 
    9053MAP7microtubule-associated protein 76q23.3Hs.486548 
    9209LRRFIP2leucine rich repeat (in FLII) interacting protein 23p22.2Hs.475319 
    9267PSCD1pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)17q25Hs.191215 
    928CD9CD9 molecule12p13.3Hs.114286 
    9380GRHPRglyoxylate reductase/hydroxypyruvate reductase9q12Hs.155742 
    94015TTYH2tweety homolog 2 (Drosophila)17q25.1Hs.27935 
    950SCARB2scavenger receptor class B, member 24q21.1Hs.349656 
    9517SPTLC2serine palmitoyltransferase, long chain base subunit 214q24.3-q31Hs.435661 
    9706ULK2unc-51-like kinase 2 (C. elegans)17p11.2Hs.168762 
    9778KIAA0232KIAA02324p16.1Hs.79276 
    10006ABI1abl-interactor 110p11.2Hs.508148 
    10252SPRY1sprouty homolog 1, antagonist of FGF signaling (Drosophila)4q28.1Hs.436944 
    10367CBARA1calcium binding atopy-related autoantigen 110q22.1Hs.524367 
    10400PEMTphosphatidylethanolamine N-methyltransferase17p11.2Hs.287717 
    10522DEAF1deformed epidermal autoregulatory factor 1 (Drosophila)11p15.5Hs.243994 
    10602CDC42EP3CDC42 effector protein (Rho GTPase binding) 32p21Hs.369574 
    10634GAS2L1growth arrest-specific 2 like 122q12.2Hs.322852 
    10983CCNIcyclin I4q21.1Hs.518827 
    11124FAF1Fas (TNFRSF6) associated factor 11p33Hs.530402 
    11231SEC63SEC63 homolog (S. cerevisiae)6q21Hs.529957 
    126328NDUFA11NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa19p13.3Hs.406062 
    147906DACT3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)19q13.32Hs.515490 
    1489CTF1cardiotrophin 116p11.2-p11.1Hs.483811 
    149175MANEALmannosidase, endo-alpha-like1p34.3Hs.534562 
    149603RNF187ring finger protein 1871q42.13Hs.356377 
    149837LOC149837-20p12.3Hs.123609 
    149998LIPIlipase, member I21q11.2Hs.139907 
    Page: 1 2 3 4 5 6 7 list all