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Dataset Description
  • Dataset Name: 16292326
  • Species: Human
  • Method: Microarray
  • No. of Genes: 303
  • Tissue: Frontal cortex
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
  • Dataset Summary: In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

    Gene list of this dataset (303 genes)
    Page: 1 2 3 4 5 6 7 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    23321TRIM2tripartite motif-containing 24q31.3Hs.435711 
    23353UNC84Aunc-84 homolog A (C. elegans)7p22.3Hs.438072 
    23387KIAA0999-11q23.3Hs.167451 
    2339FNTAfarnesyltransferase, CAAX box, alpha8p11Hs.370312 
    23405DICER1dicer 1, ribonuclease type III14q32.13Hs.87889 
    23431AP4E1adaptor-related protein complex 4, epsilon 1 subunit15q21.2Hs.413366 
    2517FUCA1fucosidase, alpha-L- 1, tissue1p34Hs.370858 
    2549GAB1GRB2-associated binding protein 14q31.21Hs.80720 
    2551GABPAGA binding protein transcription factor, alpha subunit 60kDa21q21-q22.1|21q21.3Hs.473470 
    256471MFSD8major facilitator superfamily domain containing 84q28.1-q28.2Hs.480701 
    25801GCAgrancalcin, EF-hand calcium binding protein2q24.2Hs.377894 
    25932CLIC4chloride intracellular channel 41p36.11Hs.440544 
    26035GLCEglucuronic acid epimerase15q23Hs.183006 
    26118WSB1WD repeat and SOCS box-containing 117q11.1Hs.446017 
    2618GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase21q22.1|21q22.11Hs.473648 
    26224FBXL3F-box and leucine-rich repeat protein 313q22Hs.508284 
    262AMD1adenosylmethionine decarboxylase 16q21-q22Hs.159118 
    2676GFRA3GDNF family receptor alpha 35q31.1-q31.3Hs.58042 
    26959HBP1HMG-box transcription factor 17q22-q31Hs.162032 
    2705GJB1gap junction protein, beta 1, 32kDaXq13.1Hs.333303 
    28232SLCO3A1solute carrier organic anion transporter family, member 3A115q26Hs.311187 
    285086LOC285086-2q36.3Hs.352962 
    28513CDH19cadherin 19, type 218q22-q23Hs.42771 
    285195SLC9A9solute carrier family 9 (sodium/hydrogen exchanger), member 93q24Hs.302257 
    3181HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B17p15Hs.487774 
    3475IFRD1interferon-related developmental regulator 17q22-q31Hs.7879 
    359948IRF2BP2interferon regulatory factor 2 binding protein 21q42.3Hs.350268 
    3920LAMP2lysosomal-associated membrane protein 2Xq24Hs.496684 
    400073FLJ40142-12q24.11Hs.44817 
    4008LMO7LIM domain 713q22.2Hs.207631 
    4122MAN2A2mannosidase, alpha, class 2A, member 215q26.1Hs.116459 
    4140MARK3MAP/microtubule affinity-regulating kinase 314q32.3Hs.35828 
    415118C5orf9chromosome 5 open reading frame 95q31Hs.124611 
    4174MCM5minichromosome maintenance complex component 522q13.1Hs.517582 
    4238MFAP3microfibrillar-associated protein 35q32-q33.2Hs.432818 
    4649MYO9Amyosin IXA15q22-q23Hs.546268 
    4750NEK1NIMA (never in mitosis gene a)-related kinase 14q33Hs.481181 
    4820NKTRnatural killer-tumor recognition sequence3p23-p21Hs.529509 
    50484RRM2Bribonucleotide reductase M2 B (TP53 inducible)8q23.1Hs.512592 
    50809HP1BP3heterochromatin protein 1, binding protein 31p36.12Hs.142442 
    50862RNF141ring finger protein 14111p15.4Hs.44685 
    50863HNT-11q25Hs.504352 
    51104FAM108B1family with sequence similarity 108, member B19q21.13Hs.380389 
    51604PIGTphosphatidylinositol glycan anchor biosynthesis, class T20q12-q13.12Hs.437388 
    51642MRPL48mitochondrial ribosomal protein L4811q13.4Hs.503239 
    51704GPRC5BG protein-coupled receptor, family C, group 5, member B16p12Hs.148685 
    51727CMPK1cytidine monophosphate (UMP-CMP) kinase 1, cytosolic1p32Hs.11463 
    5208PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 21q31Hs.282702 
    5287PIK3C2Bphosphoinositide-3-kinase, class 2, beta polypeptide1q32Hs.497487 
    5305PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha10p12.2Hs.57079 
    Page: 1 2 3 4 5 6 7 list all