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Gene Information
Gene ID:4649
Symbol:MYO9A
Full Name:myosin IXA
Alias:FLJ11061|FLJ13244|MGC71859
Organism:Homo sapiens (Human)
Chromosome:15
Genetic Location:15q22-q23
Physical Location:69905404-70197475 on NC_000015.8, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 270163 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.546268
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006901.2NP_008832.2NC_000015.8 range: 69905404..70197475, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016459myosin complexCellular ComponentIEA
GO:0005622intracellularCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0019992diacylglycerol bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0003774motor activityMolecular FunctionIEA
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0007601visual perceptionBiological ProcessTAS (10409426)
Other Database Cross Links
NCBI Entrez Gene:4649
HGNC:7608
Ensembl:ENSG00000066933
MIM:604875
HPRD:05341
HuGE Navigator:4649
dbSNP:MYO9A
GeneCard:MYO9A
AceView:MYO9A