ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MYO9A

Full Name:

myosin IXA

Alias:

FLJ11061|FLJ13244|MGC71859

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

15q22-q23

Physical Location:

69905404-70197475 on NC_000015.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 270163 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Hs.546268
Note:		"Class II, down-regulated gene"

Dataset Information

Name:		16292326
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:		In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006901.2	NP_008832.2	NC_000015.8 range: 69905404..70197475, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016459	myosin complex	Cellular Component	IEA
GO:0005622	intracellular	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0019992	diacylglycerol binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0003774	motor activity	Molecular Function	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0007601	visual perception	Biological Process	TAS (10409426)