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Dataset Description
  • Dataset Name: 16292326
  • Species: Human
  • Method: Microarray
  • No. of Genes: 303
  • Tissue: Frontal cortex
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
  • Dataset Summary: In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

    Gene list of this dataset (303 genes)
    Page: 1 2 3 4 5 6 7 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    157773C8orf48chromosome 8 open reading frame 488p22Hs.104941 
    157860LOC157860-8p11.23Hs.170296 
    1616DAXXdeath-associated protein 66p21.3Hs.336916 
    170394PWWP2BPWWP domain containing 2B10q26.3Hs.527751 
    1854DUTdeoxyuridine triphosphatase15q15-q21.1Hs.527980 
    190NR0B1nuclear receptor subfamily 0, group B, member 1Xp21.3-p21.2Hs.268490 
    197322ACSF3acyl-CoA synthetase family member 316q24.3Hs.461727 
    2053EPHX2epoxide hydrolase 2, cytoplasmic8p21-p12Hs.212088 
    220323OAFOAF homolog (Drosophila)11q23.3Hs.445081 
    2217FCGRTFc fragment of IgG, receptor, transporter, alpha19q13.3Hs.111903 
    223117SEMA3Dsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D7q21.11Hs.201340 
    22818COPZ1coatomer protein complex, subunit zeta 112q13.2-q13.3Hs.505652 
    22870SAPS1SAPS domain family, member 119q13.42Hs.515610 
    23024PDZRN3PDZ domain containing RING finger 33p13Hs.434900 
    23154NCDNneurochondrin1p34.3Hs.121870 
    23303KIF13Bkinesin family member 13B8p21.1Hs.444767 
    23367LARP1La ribonucleoprotein domain family, member 15q33.2Hs.292078 
    23469PHF3PHD finger protein 36q12Hs.348921 
    2526FUT4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)11q21Hs.390420 
    2550GABBR1gamma-aminobutyric acid (GABA) B receptor, 16p21.31Hs.167017 
    25833POU2F3POU class 2 homeobox 311q23.3Hs.227115 
    25876SPEF1sperm flagellar 120pter-q11.23Hs.72620 
    26018LRIG1leucine-rich repeats and immunoglobulin-like domains 13p14Hs.518055 
    26273FBXO3F-box protein 311p13Hs.406787 
    27092CACNG4calcium channel, voltage-dependent, gamma subunit 417q24Hs.514423 
    27128PSCD4pleckstrin homology, Sec7 and coiled-coil domains 422q12.3-q13.1Hs.170944 
    283385MORN3MORN repeat containing 312q24.31Hs.434154 
    284098PIGWphosphatidylinositol glycan anchor biosynthesis, class W17q12Hs.378885 
    285733LOC285733-6q23.1Hs.388715 
    29082CHMP4Achromatin modifying protein 4A14q12Hs.279761 
    29083GTPBP8GTP-binding protein 8 (putative)3q13.2Hs.127496 
    3338DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 411q13Hs.172847 
    338864LOC338864-13q21.33Hs.97408 
    3646EIF3Eeukaryotic translation initiation factor 3, subunit E8q22-q23Hs.405590 
    374354NHLRC2NHL repeat containing 210q25.3Hs.369924 
    388536ZNF790zinc finger protein 79019q13.12Hs.282067 
    401207FLJ44606-5q23.2Hs.49573 
    404744AAA1-7p14.3Hs.487951 
    4247MGAT2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase14q21Hs.93338 
    4633MYL2myosin, light chain 2, regulatory, cardiac, slow12q23-q24.3Hs.75535 
    4659PPP1R12Aprotein phosphatase 1, regulatory (inhibitor) subunit 12A12q15-q21Hs.49582 
    4782NFICnuclear factor I/C (CCAAT-binding transcription factor)19p13.3Hs.170131 
    51170HSD17B11hydroxysteroid (17-beta) dehydrogenase 114q22.1Hs.284414 
    51177PLEKHO1pleckstrin homology domain containing, family O member 11q21.2Hs.438824 
    51592TRIM33tripartite motif-containing 331p13.1Hs.26837 
    5163PDK1pyruvate dehydrogenase kinase, isozyme 12q31.1Hs.470633 
    51661FKBP7FK506 binding protein 72q31.2Hs.410378 
    51678MPP6membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)7p15Hs.533355 
    517ATP5G2ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)12q13.13Hs.524464 
    53615MBD3methyl-CpG binding domain protein 319p13.3Hs.178728 
    Page: 1 2 3 4 5 6 7 list all