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Gene Information
Gene ID:29083
Symbol:GTPBP8
Full Name:GTP-binding protein 8 (putative)
Alias:HSPC135
Organism:Homo sapiens (Human)
Chromosome:3
Genetic Location:3q13.2
Physical Location:114192489-114202910 on NC_000003.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.127496
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_014170.2NP_054889.2NC_000003.10 range: 114192489..114202910
NM_138485.1NP_612494.1NC_000003.10 range: 114192489..114202910
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005525GTP bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:29083
HGNC:25007
Ensembl:ENSG00000163607
MIM:
HPRD:13700
HuGE Navigator:29083
dbSNP:GTPBP8
GeneCard:GTPBP8
AceView:GTPBP8