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Gene Information
Gene ID:23367
Symbol:LARP1
Full Name:La ribonucleoprotein domain family, member 1
Alias:KIAA0731|LARP|MGC19556
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q33.2
Physical Location:154072654-154177357 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.292078
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_015315.3NP_056130.2NC_000005.8 range: 154072654..154177357
NM_033551.2NP_291029.2NC_000005.8 range: 154072654..154177357
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0003723RNA bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
Other Database Cross Links
NCBI Entrez Gene:23367
HGNC:29531
Ensembl:ENSG00000155506
MIM:612059
HPRD:11225
HuGE Navigator:23367
dbSNP:LARP1
GeneCard:LARP1
AceView:LARP1