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Gene Information
Gene ID:51678
Symbol:MPP6
Full Name:membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Alias:PALS2|VAM-1|VAM1|p55T
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7p15
Physical Location:24579609-24694022 on NC_000007.12
Gene Type:protein-coding
Orthologs:This gene has Rat: 362359 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.533355
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016447.2NP_057531.2NC_000007.12 range: 24579609..24694022
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentNAS (11311936)
GO:0005515protein bindingMolecular FunctionIPI (11311936)
GO:0006461protein complex assemblyBiological ProcessNAS (11311936)
Other Database Cross Links
NCBI Entrez Gene:51678
HGNC:18167
Ensembl:ENSG00000105926
MIM:606959
HPRD:09509
HuGE Navigator:51678
dbSNP:MPP6
GeneCard:MPP6
AceView:MPP6