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Dataset Description
  • Dataset Name: 16292326
  • Species: Human
  • Method: Microarray
  • No. of Genes: 303
  • Tissue: Frontal cortex
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
  • Dataset Summary: In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

    Gene list of this dataset (303 genes)
    Page: 1 2 3 4 5 6 7 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    5362PLXNA2plexin A21q32.2Hs.497626 
    54067C21orf49chromosome 21 open reading frame 4921q22.11Hs.54725 
    5411PNNpinin, desmosome associated protein14q21.1Hs.409965 
    54531MIER2mesoderm induction early response 1, family member 219p13.3Hs.101891 
    54543TOMM7translocase of outer mitochondrial membrane 7 homolog (yeast)7p15.3Hs.112318 
    54897CASZ1castor zinc finger 11p36.22Hs.439894 
    55214LEPREL1leprecan-like 13q28Hs.374191 
    5570PKIBprotein kinase (cAMP-dependent, catalytic) inhibitor beta6q22.31Hs.486354 
    55970GNG12guanine nucleotide binding protein (G protein), gamma 121p31.3Hs.431101 
    5682PSMA1proteasome (prosome, macropain) subunit, alpha type, 111p15.1Hs.102798 
    56998CTNNBIP1catenin, beta interacting protein 11p36.22Hs.463759 
    5719PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 1311p15.5Hs.134688 
    5747PTK2PTK2 protein tyrosine kinase 28q24-qterHs.395482 
    57492ARID1BAT rich interactive domain 1B (SWI1-like)6q25.1Hs.291587 
    57560IFT80intraflagellar transport 80 homolog (Chlamydomonas)3q26.1Hs.478095 
    5764PTNpleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)7q33-q34Hs.371249 
    5932RBBP8retinoblastoma binding protein 818q11.2Hs.546282 
    5991RFX3regulatory factor X, 3 (influences HLA class II expression)9p24.2Hs.136829 
    6164RPL34ribosomal protein L344q25Hs.438227 
    63874ABHD4abhydrolase domain containing 414q11.2Hs.445665 
    64083GOLPH3golgi phosphoprotein 3 (coat-protein)5p13.3Hs.408909 
    64852TUT1terminal uridylyl transferase 1, U6 snRNA-specific11q12.2Hs.256184 
    6539SLC6A12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 1212p13Hs.437174 
    6574SLC20A1solute carrier family 20 (phosphate transporter), member 12q11-q14Hs.187946 
    6731SRP72signal recognition particle 72kDa4q11Hs.237825 
    7167TPI1triosephosphate isomerase 112p13Hs.524219 
    725C4BPBcomplement component 4 binding protein, beta1q32Hs.99886 
    7443VRK1vaccinia related kinase 114q32Hs.422662 
    770CA11carbonic anhydrase XI19q13.3Hs.428446 
    79149ZSCAN5zinc finger and SCAN domain containing 519q13.43Hs.177688 
    7916BAT2HLA-B associated transcript 26p21.3Hs.436093 
    79751SLC25A22solute carrier family 25 (mitochondrial carrier: glutamate), member 2211p15.5Hs.99486 
    79915ATAD5ATPase family, AAA domain containing 517q11.2Hs.528902 
    79979CXorf34chromosome X open reading frame 34Xq22.1Hs.496501 
    8013NR4A3nuclear receptor subfamily 4, group A, member 39q22Hs.279522 
    81559TRIM11tripartite motif-containing 111q42.13Hs.13543 
    84243ZDHHC18zinc finger, DHHC-type containing 181p36.11Hs.523710 
    8454CUL1cullin 17q36.1Hs.146806 
    84669USP32ubiquitin specific peptidase 3217q23.2Hs.132868 
    84675TRIM55tripartite motif-containing 558q13.1Hs.85524 
    85415RHPN2rhophilin, Rho GTPase binding protein 219q13.11Hs.466435 
    8566PDXKpyridoxal (pyridoxine, vitamin B6) kinase21q22.3Hs.284491 
    8615USO1USO1 homolog, vesicle docking protein (yeast)4q21.1Hs.292689 
    8756ADAM7ADAM metallopeptidase domain 78p21.2Hs.116147 
    8829NRP1neuropilin 110p12Hs.131704 
    9040UBE2Mubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)19q13.43Hs.406068 
    9117SEC22CSEC22 vesicle trafficking protein homolog C (S. cerevisiae)3p22.1Hs.445892 
    91461LOC91461-2p21Hs.408542 
    9209LRRFIP2leucine rich repeat (in FLII) interacting protein 23p22.2Hs.475319 
    9296ATP6V1FATPase, H+ transporting, lysosomal 14kDa, V1 subunit F7q32Hs.78089 
    Page: 1 2 3 4 5 6 7 list all