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Gene Information
Gene ID:85415
Symbol:RHPN2
Full Name:rhophilin, Rho GTPase binding protein 2
Alias:RhoBP|p76RBE
Organism:Homo sapiens (Human)
Chromosome:19
Genetic Location:19q13.11
Physical Location:38161337-38247633 on NC_000019.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.466435
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_033103.3NP_149094.2NC_000019.8 range: 38161337..38247633, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
GO:0007165signal transductionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:85415
HGNC:19974
Ensembl:ENSG00000131941
MIM:
HPRD:10192
HuGE Navigator:85415
dbSNP:RHPN2
GeneCard:RHPN2
AceView:RHPN2