Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:84243
Symbol:ZDHHC18
Full Name:zinc finger, DHHC-type containing 18
Alias:DKFZp667O2416
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1p36.11
Physical Location:27025787-27054794 on NC_000001.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.523710
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_032283.1NP_115659.1NC_000001.9 range: 27025787..27054794
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0008415acyltransferase activityMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:84243
HGNC:20712
Ensembl:ENSG00000204160
MIM:
HPRD:15713
HuGE Navigator:84243
dbSNP:ZDHHC18
GeneCard:ZDHHC18
AceView:ZDHHC18