ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SLC20A1

Full Name:

solute carrier family 20 (phosphate transporter), member 1

Alias:

DKFZp686J2397|FLJ41426|GLVR1|Glvr-1|PIT1|PiT-1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2q11-q14

Physical Location:

113119997-113137872 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Hs.187946
Note:		"Class II, up-regulated gene"

Dataset Information

Name:		16292326
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:		In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005415.3	NP_005406.3	NC_000002.10 range: 113119997..113137872

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8041748)
GO:0016020	membrane	Cellular Component	TAS (8041748)
GO:0004872	receptor activity	Molecular Function	TAS (8041748)
GO:0005315	inorganic phosphate transmembrane transporter activity	Molecular Function	IEA
GO:0005436	sodium:phosphate symporter activity	Molecular Function	TAS (8041748)
GO:0015293	symporter activity	Molecular Function	IEA
GO:0006817	phosphate transport	Biological Process	IEA
GO:0006810	transport	Biological Process	TAS (8041748)
GO:0006796	phosphate metabolic process	Biological Process	TAS (8041748)
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IMP (12761501)