Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:220323
Symbol:OAF
Full Name:OAF homolog (Drosophila)
Alias:MGC52117|NS5ATP13TP2
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q23.3
Physical Location:119586956-119605859 on NC_000011.8
Gene Type:protein-coding
Orthologs:This gene has Mouse: 102644 Fly: 33435 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.445081
Note:"Class II, up-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_178507.2NP_848602.1NC_000011.8 range: 119586956..119605859
Other Database Cross Links
NCBI Entrez Gene:220323
HGNC:28752
Ensembl:ENSG00000184232
MIM:
HPRD:17646
HuGE Navigator:220323
dbSNP:OAF
GeneCard:OAF
AceView:OAF