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Gene Information
Gene ID:85476
Symbol:GFM1
Full Name:G elongation factor, mitochondrial 1
Alias:COXPD1|EFG|EFG1|EFGM|EGF1|FLJ12662|FLJ13632|FLJ20773|GFM|hEFG1
Organism:Homo sapiens (Human)
Chromosome:3
Genetic Location:3q25.1-q26.2
Physical Location:159845010-159893054 on NC_000003.10
Gene Type:protein-coding
Orthologs:This gene has Rat: 114017 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.518355
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_024996.5NP_079272.4NC_000003.10 range: 159845010..159893054
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003746translation elongation factor activityMolecular FunctionIEA
GO:0003924GTPase activityMolecular FunctionIEA
GO:0005525GTP bindingMolecular FunctionIEA
GO:0006414translational elongationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:85476
HGNC:13780
Ensembl:ENSG00000168827
MIM:606639
HPRD:07365
HuGE Navigator:85476
dbSNP:GFM1
GeneCard:GFM1
AceView:GFM1