ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gfm1

Full Name:

G elongation factor, mitochondrial 1

Alias:

EF-G|Efg|Gfm|MGC93294

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

2q31

Physical Location:

157283045-157327968 on NC_005101.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 85476 Symbol (Name): GFM1 (G elongation factor, mitochondrial 1)

Ortholog Status:

The human GeneID 85476 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		17517326
Method:		Microarray
Tissue:		Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:		The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_053625.1	NP_446077.1	NC_005101.2 range: 157283045..157327968

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005739	mitochondrion	Cellular Component	ISS
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0003746	translation elongation factor activity	Molecular Function	IEA
GO:0003924	GTPase activity	Molecular Function	IEA
GO:0005525	GTP binding	Molecular Function	IEA
GO:0006414	translational elongation	Biological Process	IEA