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Gene Information
Gene ID:11086
Symbol:ADAM29
Full Name:ADAM metallopeptidase domain 29
Alias:svph1
Organism:Homo sapiens (Human)
Chromosome:4
Genetic Location:4q34
Physical Location:176076133-176135905 on NC_000004.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.126838
Note:"Class I, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_014269.3NP_055084.3NC_000004.10 range: 176076133..176135905
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005887integral to plasma membraneCellular ComponentTAS (10512762)
GO:0016020membraneCellular ComponentIEA
GO:0004222metalloendopeptidase activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0006508proteolysisBiological ProcessIEA
GO:0007283spermatogenesisBiological ProcessTAS (10512762)
Other Database Cross Links
NCBI Entrez Gene:11086
HGNC:207
Ensembl:ENSG00000168594
MIM:604778
HPRD:05306
HuGE Navigator:11086
dbSNP:ADAM29
GeneCard:ADAM29
AceView:ADAM29