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Gene Information
Gene ID:2993
Symbol:GYPA
Full Name:glycophorin A (MNS blood group)
Alias:CD235a|GPA|GPErik|GPSAT|GpMiIII|HGpMiIII|HGpMiV|HGpMiX|HGpMiXI|HGpSta(C)|MN|MNS
Organism:Homo sapiens (Human)
Chromosome:4
Genetic Location:4q28.2-q31.1
Physical Location:145249905-145281293 on NC_000004.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.434973
Note:"Class I, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Information
Original ID1:GYPA
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002099.4NP_002090.2NC_000004.10 range: 145249905..145281293, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0005624membrane fractionCellular ComponentTAS (3456608)
GO:0005886plasma membraneCellular ComponentTAS (8245024)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0003674molecular_functionMolecular FunctionND
GO:0042802identical protein bindingMolecular FunctionIPI (14681217)
GO:0008150biological_processBiological ProcessND
Other Database Cross Links
NCBI Entrez Gene:2993
HGNC:4702
Ensembl:ENSG00000170180
MIM:111300
HPRD:07508
HuGE Navigator:2993
dbSNP:GYPA
GeneCard:GYPA
AceView:GYPA