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Gene Information
Gene ID:114885
Symbol:OSBPL11
Full Name:oxysterol binding protein-like 11
Alias:FLJ13012|FLJ13164|ORP-11|ORP11|OSBP12|TCCCIA00292
Organism:Homo sapiens (Human)
Chromosome:3
Genetic Location:3q21
Physical Location:126730391-126796628 on NC_000003.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.477440
Note:"Class I, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022776.3NP_073613.2NC_000003.10 range: 126730391..126796628, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0006869lipid transportBiological ProcessIEA
GO:0008202steroid metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:114885
HGNC:16397
Ensembl:ENSG00000144909
MIM:606739
HPRD:09481
HuGE Navigator:114885
dbSNP:OSBPL11
GeneCard:OSBPL11
AceView:OSBPL11