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Gene Information
Gene ID:11083
Symbol:DIDO1
Full Name:death inducer-obliterator 1
Alias:BYE1|C20orf158|DATF1|DIDO2|DIDO3|DIO-1|DIO1|DKFZp434P1115|FLJ11265|KIAA0333|MGC16140|dJ885L7.8
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q13.33
Physical Location:60979534-61039718 on NC_000020.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.517172
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022105.3NP_071388.2NC_000020.9 range: 60979534..61039718, complement
NM_033081.1NP_149072.1NC_000020.9 range: 60979534..61039718, complement
NM_080796.2NP_542986.1NC_000020.9 range: 60979534..61039718, complement
NM_080797.2NP_542987.2NC_000020.9 range: 60979534..61039718, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0006915apoptosisBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:11083
HGNC:2680
Ensembl:ENSG00000101191
MIM:604140
HPRD:10363
HuGE Navigator:11083
dbSNP:DIDO1
GeneCard:DIDO1
AceView:DIDO1