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Gene Information
Gene ID:23041
Full Name:MON2 homolog (S. cerevisiae)
Organism:Homo sapiens (Human)
Genetic Location:12q14.1
Physical Location:61146863-61277629 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.389378
Note:"Class II, down-regulated gene"
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_015026.2NP_055841.2NC_000012.10 range: 61146863..61277629
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentIEA
GO:0045263proton-transporting ATP synthase complex, coupling factor F(o)Cellular ComponentIEA
GO:0031966mitochondrial membraneCellular ComponentIEA
GO:0016469proton-transporting two-sector ATPase complexCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0046933hydrogen ion transporting ATP synthase activity, rotational mechanismMolecular FunctionIEA
GO:0005488bindingMolecular FunctionIEA
GO:0046961hydrogen ion transporting ATPase activity, rotational mechanismMolecular FunctionIEA
GO:0015992proton transportBiological ProcessIEA
GO:0015986ATP synthesis coupled proton transportBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
GO:0006895Golgi to endosome transportBiological ProcessISS
GO:0006811ion transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:23041
HuGE Navigator:23041