| Gene Information |
| Gene ID: | | 10922 |
| Symbol: | | FASTK |
| Full Name: | | Fas-activated serine/threonine kinase |
| Alias: | | FAST |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 7 |
| Genetic Location: | | 7q35 |
| Physical Location: | | 150404640-150408883 on NC_000007.12, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | X86779 | | Fold Change: | | -2.44 |
| | Dataset Information | | Name: | | 15236863 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed | | Summary: | | We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0004672 | protein kinase activity | Molecular Function | IEA | |
| GO:0005524 | ATP binding | Molecular Function | IEA | |
| GO:0016301 | kinase activity | Molecular Function | IEA | |
| GO:0016740 | transferase activity | Molecular Function | IEA | |
| GO:0033867 | Fas-activated serine/threonine kinase activity | Molecular Function | IEA | |
| GO:0006468 | protein amino acid phosphorylation | Biological Process | TAS (7544399) | |
| GO:0006915 | apoptosis | Biological Process | IEA | |
| GO:0007165 | signal transduction | Biological Process | TAS (7544399) | |
| GO:0008624 | induction of apoptosis by extracellular signals | Biological Process | TAS (7544399) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 10922 |
| HGNC: | | 24676 |
| Ensembl: | | ENSG00000164896 |
| MIM: | | 606965 |
| HPRD: | | 07368 |
| HuGE Navigator: | | 10922 |
| dbSNP: | | FASTK |
| GeneCard: | | FASTK |
| AceView: | | FASTK |
