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Gene Information
Gene ID:10955
Symbol:SERINC3
Full Name:serine incorporator 3
Alias:AIGP1|DIFF33|SBBI99|TDE|TDE1|TMS-1
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q13.1-q13.3
Physical Location:42558277-42584139 on NC_000020.9, complement
Gene Type:protein-coding
Orthologs:This gene has Rat: 296350 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006811.2NP_006802.1NC_000020.9 range: 42558277..42584139, complement
NM_198941.1NP_945179.1NC_000020.9 range: 42558277..42584139, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentTAS (10559794)
GO:0005515protein bindingMolecular FunctionIPI (17353931)
Other Database Cross Links
NCBI Entrez Gene:10955
HGNC:11699
Ensembl:ENSG00000132824
MIM:607165
HPRD:06201
HuGE Navigator:10955
dbSNP:SERINC3
GeneCard:SERINC3
AceView:SERINC3