ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Chrna5

Full Name:

cholinergic receptor, nicotinic, alpha polypeptide 5

Alias:

Acra-5|Acra5|MGC124059|MGC124168

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 B|9 32.0 cM

Physical Location:

54834429-54854381 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1138 Symbol (Name): CHRNA5 (cholinergic receptor, nicotinic, alpha 5)

Ortholog Status:

The human GeneID 1138 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_176844.3	NP_789814.2	NC_000075.5 range: 54834429..54854381

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	Cellular Component	IPI (17434683)
GO:0005230	extracellular ligand-gated ion channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0030594	neurotransmitter receptor activity	Molecular Function	IEA
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0035094	response to nicotine	Biological Process	IMP (9495872)