ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

LYST

Full Name:

lysosomal trafficking regulator

Alias:

CHS|CHS1

Organism:

Homo sapiens (Human)

Chromosome:

1

Genetic Location:

1q42.1-q42.2

Physical Location:

233890965-234096842 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		U67615
Fold Change:		2.1

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000081.2	NP_000072.2	NC_000001.9 range: 233890965..234096842, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005768	endosome	Cellular Component	TAS (9606205)
GO:0015630	microtubule cytoskeleton	Cellular Component	TAS (9606205)
GO:0006968	cellular defense response	Biological Process	TAS (6445041)
GO:0007165	signal transduction	Biological Process	TAS (8717042)
GO:0008333	endosome to lysosome transport	Biological Process	TAS (9606205)
GO:0015031	protein transport	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000143669

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: