ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CHRNA1

Full Name:

cholinergic receptor, nicotinic, alpha 1 (muscle)

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2q24-q32

Physical Location:

175320565-175337426 on NC_000002.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11435 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CHRNA1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0031594	neuromuscular junction	Cellular Component	IDA (9221765)
GO:0030054	cell junction	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex	Cellular Component	TAS (7619526)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0015464	acetylcholine receptor activity	Molecular Function	TAS (7619526)
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity	Molecular Function	IMP (9221765)
GO:0005230	extracellular ligand-gated ion channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	TAS (6688857)
GO:0007165	signal transduction	Biological Process	TAS (7619526)
GO:0007528	neuromuscular junction development	Biological Process	IMP (9221765)
GO:0006936	muscle contraction	Biological Process	TAS (7619526)
GO:0006811	ion transport	Biological Process	IEA
GO:0042391	regulation of membrane potential	Biological Process	IMP (9221765)
GO:0007274	neuromuscular synaptic transmission	Biological Process	IMP (9221765)