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Gene Information
Gene ID:11435
Symbol:Chrna1
Full Name:cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Alias:AI385656|AI608266|Achr-1|Acra
Organism:Mus musculus (Mouse)
Chromosome:2
Genetic Location:2 C3|2 43.0 cM
Physical Location:73401337-73418362 on NC_000068.6, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 1134    Symbol (Name): CHRNA1 (cholinergic receptor, nicotinic, alpha 1 (muscle))
Ortholog Status:The human GeneID 1134 is also in human dataset(s).
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Etact1Alcohol Stimulated Activity25141-61 (cM)3.92.20E-05SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_007389.4NP_031415.2NC_000068.6 range: 73401337..73418362, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0030054cell junctionCellular ComponentIEA
GO:0005892nicotinic acetylcholine-gated receptor-channel complexCellular ComponentIPI (8910344)
GO:0005886plasma membraneCellular ComponentIDA (12388596)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0031594neuromuscular junctionCellular ComponentIDA (16203963)
GO:0031594neuromuscular junctionCellular ComponentISO
GO:0045202synapseCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0030594neurotransmitter receptor activityMolecular FunctionIEA
GO:0042166acetylcholine bindingMolecular FunctionIGI (8910344)
GO:0004872receptor activityMolecular FunctionIEA
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityMolecular FunctionIGI (2383398)
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityMolecular FunctionISO
GO:0005216ion channel activityMolecular FunctionIEA
GO:0005230extracellular ligand-gated ion channel activityMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
GO:0006811ion transportBiological ProcessIEA
GO:0042391regulation of membrane potentialBiological ProcessIGI (2383398)
GO:0042391regulation of membrane potentialBiological ProcessISO
GO:0007274neuromuscular synaptic transmissionBiological ProcessISO
GO:0007528neuromuscular junction developmentBiological ProcessISO
Other Database Cross Links
NCBI Entrez Gene:11435
MGI:
Ensembl:ENSMUSG00000027107
dbSNP:Chrna1
AceView:Chrna1