ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Accn1

Full Name:

amiloride-sensitive cation channel 1, neuronal (degenerin)

Alias:

ACIC2|ASIC2|BNC1|BNaC1a|Mdeg

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B5|11 42.0 cM

Physical Location:

80693666-81781897 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 40 Symbol (Name): ACCN1 (amiloride-sensitive cation channel 1, neuronal (degenerin))

Ortholog Status:

The human GeneID 40 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043025	cell soma	Cellular Component	IDA (15537887)
GO:0043005	neuron projection	Cellular Component	IDA (15537887)
GO:0016020	membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	IDA (11306621\|11854527)
GO:0016021	integral to membrane	Cellular Component	IDA (9368048)
GO:0005261	cation channel activity	Molecular Function	IMP (11854527)
GO:0005261	cation channel activity	Molecular Function	IDA (11854527)
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0015280	amiloride-sensitive sodium channel activity	Molecular Function	IDA (9368048\|11306621)
GO:0031402	sodium ion binding	Molecular Function	IEA
GO:0005272	sodium channel activity	Molecular Function	IEA
GO:0001101	response to acid	Biological Process	IDA (11306621\|11854527)
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (14762118)
GO:0009612	response to mechanical stimulus	Biological Process	IMP (11069180)
GO:0007605	sensory perception of sound	Biological Process	IMP (15537887)
GO:0007602	phototransduction	Biological Process	IMP (14762118)
GO:0006814	sodium ion transport	Biological Process	IDA (9368048\|11306621)
GO:0006812	cation transport	Biological Process	IMP (11854527)
GO:0006812	cation transport	Biological Process	IDA (11854527)
GO:0006811	ion transport	Biological Process	IEA
GO:0006810	transport	Biological Process	IEA
GO:0001101	response to acid	Biological Process	IMP (11854527)
GO:0050974	detection of mechanical stimulus involved in sensory perception	Biological Process	IMP (11069180)