ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Bat1a

Full Name:

HLA-B-associated transcript 1A

Alias:

Bat1|p47

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

20p12

Physical Location:

3611127-3623526 on NC_005119.2, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7919 Symbol (Name): BAT1 (HLA-B associated transcript 1)

Ortholog Status:

The human GeneID 7919 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Bat1a
Fold Change:		1.13
P Value:		0.009
Note:		Differential expression between ethanol and water groups in nucleus accumbens

Dataset Information

Name:		18405950
Method:		Microarray
Tissue:		Nucleus accumbens and amygdala
Phenotype:		Ethanol self-administration, alcohol-preferring
Publication:		Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:		The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_133300.2	NP_579834.2	NC_005119.2 range: 3611127..3623526, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005681	spliceosome	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008026	ATP-dependent helicase activity	Molecular Function	IEA
GO:0042802	identical protein binding	Molecular Function	ISS
GO:0005524	ATP binding	Molecular Function	IEA
GO:0003723	RNA binding	Molecular Function	IEA
GO:0006406	mRNA export from nucleus	Biological Process	ISS
GO:0008380	RNA splicing	Biological Process	IEA
GO:0000398	nuclear mRNA splicing, via spliceosome	Biological Process	ISS
GO:0006397	mRNA processing	Biological Process	IEA