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Dataset Description
  • Dataset Name: 18405950
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 444
  • Tissue: Nucleus accumbens and amygdala
  • Phenotype: Ethanol self-administration, alcohol-preferring
  • Publication: Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
  • Dataset Summary: The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.

    Gene list of this dataset (444 genes)
    Page: 1 2 3 4 5 6 7 8 9 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    81745Pdpk13-phosphoinositide dependent protein kinase-110q12Pdpk1 
    29595Htr2a5-hydroxytryptamine (serotonin) receptor 2A15q11Htr2a 
    25689Htr5a5-hydroxytryptamine (serotonin) receptor 5A4q11Htr5a 
    308923Ahi1Abelson helper integration site 11p12Ahi1 
    81635Adaradenosine deaminase, RNA-specific2q34Adar 
    246284Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)Xq31Atrx 
    303396Appbp2amyloid beta precursor protein (cytoplasmic tail) binding protein 210q26Appbp2 
    24180Agtr1aangiotensin II receptor, type 1a17q12Agtr1a 
    25378Amhanti-Mullerian hormone7q11Amh 
    84479Ap1gbp1AP1 gamma subunit binding protein 110q26Ap1gbp1 
    313231Alg2asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)5q22Alg2 
    313231Alg2asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)5q22Alg2 
    60331Atxn3ataxin 36q32Atxn3 
    29600Atp2b4ATPase, Ca++ transporting, plasma membrane 413q13Atp2b4 
    499356BlnkB-cell linker1q54Blnk 
    24888Bcl2l1Bcl2-like 13q41.2Bcl2l1 
    64625BidBH3 interacting domain death agonist4q42Bid 
    25399Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 14q11Cacna2d1 
    58942Cacnb4calcium channel, voltage-dependent, beta 4 subunit3q12Cacnb4 
    25050Camk4calcium/calmodulin-dependent protein kinase IV18p12Camk4 
    171394Clstn2calsyntenin 28q31Clstn2 
    58822Csnk1ecasein kinase 1, epsilon7q34Csnk1e 
    311670Cstf1cleavage stimulation factor, 3' pre-RNA, subunit 13q42Cstf1 
    60447Clockcircadian locomoter output cycles kaput14p11Clock 
    83824Cxxc4CXXC finger 42q43Cxxc4 
    84389Ccnhcyclin H-Ccnh 
    24255Cftrcystic fibrosis transmembrane conductance regulator homolog4q21Cftr 
    500892Cyp11b1cytochrome P450, subfamily 11B, polypeptide 17q34Cyp11b1 
    64014Dusp12dual specificity phosphatase 1213q24Dusp12 
    25450Gabrb1gamma-aminobutyric acid (GABA-A) receptor, subunit beta 114p11Gabrb1 
    25451Gabrb2gamma-aminobutyric acid (GABA-A) receptor, subunit beta 210q21Gabrb2 
    24414Grm1glutamate receptor, metabotropic 11p13Grm1 
    24379Gad1glutamic acid decarboxylase 13q21Gad1 
    84027Gsk3bglycogen synthase kinase 3 beta11q21Gsk3b 
    81666Gnaqguanine nucleotide binding protein, alpha q polypeptide1q43Gnaq 
    81666Gnaqguanine nucleotide binding protein, alpha q polypeptide1q43Gnaq 
    497198Impactimprinted and ancient-Impact 
    307644Kifc3kinesin family member C319p13Kifc3 
    311456MkksMcKusick-Kaufman syndrome protein3q36Mkks 
    29456Map1bmicrotubule-associated protein 1b2q12Map1b 
    302983Mapk8ip3mitogen-activated protein kinase 8 interacting protein 310q12Mapk8ip3 
    361285Mllt10myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog (Drosophila)17q12.3Mllt10 
    252942Myh8myosin, heavy polypeptide 8, skeletal muscle, perinatal10q24Myh8 
    259274Nmt1N-myristoyltransferase 110q32.1Nmt1 
    25489Nedd4neural precursor cell expressed, developmentally down-regulated gene 48q24Nedd4a 
    298342NkapNFKB activating proteinXq12Nkap 
    25497Npap60nuclear pore associated protein7q34Npap60 
    25497Npap60nuclear pore associated protein7q34Npap60 
    171435P34p34 protein8q24P34 
    170636Pnma1paraneoplastic antigen MA16q31Pnma1 
    Page: 1 2 3 4 5 6 7 8 9 list all